6-[5-AMINO-6-(2-ETHOXYETHOXY)-IMIDAZO[4,5-B]PYRIDIN-3-YL]-NICOTINONITRILE DERIVATIVES AND THEIR USE AS IRAK INHIBITORS

The present invention relates to compounds inhibiting IRAK family kinases, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, autoimmune diseases and/or proliferative d...

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Main Authors BRYS, Reginald Christophe Xavier, LABÉGUÈRE, Frédéric Gilbert, MENET, Christel Jeanne Marie, MAMMOLITI, Oscar, LEFRANÇOIS, Jean-Michel, DOYON, Julien Georges Pierre-Olivier, JONCOUR, Agnès Marie, SCHMITT, Benoît Antoine, VAN DER PLAS, Steven Emiel, GENEY, Raphaël Jean Joël
Format Patent
LanguageEnglish
Published 25.10.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds inhibiting IRAK family kinases, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, autoimmune diseases and/or proliferative diseases by administering the compound of the invention.
Bibliography:Application Number: US201615769260