LOW MOLECULAR WEIGHT DERIVATIVES OF CARBOXAMIDE HALOGENATED PORPHYRINS, NAMELY CHLORINS AND BACTERIOCHLORINS, AND THEIR APPLICATIONS THEREOF

The present invention relates to carboxamide halogenated porphyrin derivatives, in particular bacteriochlorin or chlorin, of formula (I) use of the same or a pharmaceutically acceptable salt thereof in photodynamic therapy, where the derivatives are able to detect and exhibit the presence of hyperpr...

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Main Authors SCHABERLE, Fabio Antonio, MIGUENS PEREIRA, Maria, REIS DE ABREU, Artur Carios, FERRAZ CARDOSO SOARES, Helder Tao, BORGES ROCHA, Luis Gabriel, PEREIRA NASCIMENTO COSTA, Goncalo, PEREIRA MONTEIRO, Carlos Jorge, FERREIRA GONCALVES, Nuno Paulo, DA SILVA ARNAUT MOREIRA, Luis Guilherme
Format Patent
LanguageEnglish
Published 04.10.2018
Subjects
CHEMISTRY
DIAGNOSIS
ELECTROTHERAPY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
MAGNETOTHERAPY
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
RADIATION THERAPY
SURGERY
ULTRASOUND THERAPY
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Summary:The present invention relates to carboxamide halogenated porphyrin derivatives, in particular bacteriochlorin or chlorin, of formula (I) use of the same or a pharmaceutically acceptable salt thereof in photodynamic therapy, where the derivatives are able to detect and exhibit the presence of hyperproliferative disorders and, in the presence of an adequate lighting, to treat the same. The present invention also describes a pharmaceutical composition having the carboxamide halogenated porphyrin derivatives, in particular bacteria-chlorin or chlorin, of Formula (I) or a pharmaceutically acceptable salt thereof, for the treatment of cancer and/or microbial and/or viral infections, in humans or animals.
Bibliography:Application Number: US201615570956