INHIBITORS OF RETINALDEHYDE DEHYDROGENASES AND METHODS OF USE

Compounds having inhibitory activity against retinaldehyde dehydrogenases (RALDHs). The compounds can be used, for example, to inhibit synthesis of retinoic acid for the treatment of refractive error disorders such as myopia, and as infertility treatments by inhibiting spermatogenesis.

Saved in:
Bibliographic Details
Main Authors MATHER, Tim, LE, Anh Thi Quynh, BURGETT, Anthony, HARPER, Angelica R, SUMMERS, Jody A
Format Patent
LanguageEnglish
Published 13.09.2018
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:Compounds having inhibitory activity against retinaldehyde dehydrogenases (RALDHs). The compounds can be used, for example, to inhibit synthesis of retinoic acid for the treatment of refractive error disorders such as myopia, and as infertility treatments by inhibiting spermatogenesis.
Bibliography:Application Number: US201615758555