METHOD FOR PRODUCING RNA COMPOSITIONS

The present invention relates to a method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or polycationic compound, advantageously on a large scale suitable for pharmaceutical applications. The present invention further concerns the...

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Bibliographic Details
Main Authors KREUZ, Markus, SEWING, Stefanie, WIGGENHORN, Michael, EBER, Fabian Johannes, MUTZKE, Thorsten, WAGNER, Wenke, KOLLAND, Katharina, SONNTAG, Michael
Format Patent
LanguageEnglish
Published 02.08.2018
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to a method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or polycationic compound, advantageously on a large scale suitable for pharmaceutical applications. The present invention further concerns the use of the inventive method in the manufacture of a medicament or a vaccine. Furthermore, the invention relates to compositions containing the RNA-comprising nanoparticle, and to pharmaceutical compositions comprising the same.
Bibliography:Application Number: US201615566010