Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV

Disclosed is a process for the preparation of certain intermediates, e.g. those in the scheme below: which intermediates and processes are useful in the preparation of the macrocyclic HVC inhibitor Simeprevir.

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Bibliographic Details
Main Authors Ormerod Dominic John, Hermant Sébastien Nicolas J, Moody Thomas Shaw, Depré Dominique Paul Michel, Vriamont Nicolas, Brossat Maude, Riant Olivier, Lemaire Sébastien Francois Emmanuel, Horvath Andras
Format Patent
LanguageEnglish
Published 05.04.2018
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Disclosed is a process for the preparation of certain intermediates, e.g. those in the scheme below: which intermediates and processes are useful in the preparation of the macrocyclic HVC inhibitor Simeprevir.
Bibliography:Application Number: US201615559910