PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE

The present application relates to novel substituted piperidinylpyrazolopyrimidinones, to processes for their preparation, the compounds for use alone or in combinations in a method for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of acute and recu...

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Main Authors KÖLLNBERGER Maria, CANCHO GRANDE Yolanda, ELLERMANN Manuel, KÖBBERLING Johannes, STEGMANN Christian, SCHLEMMER Karl-Heinz, BEYER Kristin, KINZEL Tom, MEYER Imke, HENGEVELD Willem Jan, HAßFELD Jorma, STAMPFUß Jan, WERNER Matthias, SPERZEL Michael, BURKHARDT Nils, RÖHRIG Susanne, VALOT Gaelle, SCHUHMACHER Joachim, HEIERMANN Jörg
Format Patent
LanguageEnglish
Published 23.11.2017
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Summary:The present application relates to novel substituted piperidinylpyrazolopyrimidinones, to processes for their preparation, the compounds for use alone or in combinations in a method for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of acute and recurrent bleeding in patients with or without underlying hereditary or acquired hemostatic disorders, wherein the bleeding is associated with a disease or medical intervention selected from the group consisting of heavy menstrual bleeding, postpartum hemorrhage, hemorrhagic shock, hemorrhagic cystitis, gastrointestinal hemorrhage, trauma, surgery, transplantation, stroke, liver diseases, hereditary angioedema, nosebleed, and synovitis and cartilage damage following hemarthrosis.
Bibliography:Application Number: US201515523954