Oral Biofilm Models and Uses Thereof

The present disclosure provides an oral biofilm model including a substrate including a first surface, a second surface, and a plurality of specimens fixedly attached to the first surface, wherein an oral biofilm is capable of forming on the specimen. The surface roughness of at least one of the spe...

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Bibliographic Details
Main Authors REGE Aarti, Rinaudi Marron Luciana, SANTARPIA Ralph Peter, SURIANO David, SULLIVAN Richard
Format Patent
LanguageEnglish
Published 31.08.2017
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:The present disclosure provides an oral biofilm model including a substrate including a first surface, a second surface, and a plurality of specimens fixedly attached to the first surface, wherein an oral biofilm is capable of forming on the specimen. The surface roughness of at least one of the specimens of the plurality is less than or greater than a surface roughness of at least a second specimen of the plurality. The oral biofilm model also includes a body having sides and a bottom defining a vessel. The body is adapted to receive the substrate and the plurality of specimens and is further adapted to receive a fluid. Methods of forming oral biofilms and methods for identifying an agent for reducing or inhibiting biofilm formation are also provided.
Bibliography:Application Number: US201415512125