BISPECIFIC ANTIBODIES WITH TETRAVALENCY FOR A COSTIMULATORY TNF RECEPTOR

The invention relates to novel bispecific antigen binding molecules, comprising (a) four moieties capable of specific binding to a costimulatory TNF receptor family member, (b) at least one moiety capable of specific binding to a target cell antigen, and (c) a Fc domain composed of a first and a sec...

Full description

Saved in:
Bibliographic Details
Main Authors BRUENKER PETER, FERRARA KOLLER CLAUDIA, LEVITSKI VIKTOR, GRAU-RICHARDS SANDRA, KLEIN CHRISTIAN, UMANA PABLO, AMANN MARIA, MOSER SAMUEL, CLAUS CHRISTINA, HOSSE RALF
Format Patent
LanguageEnglish
Published 31.08.2017
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
Online AccessGet full text

Cover

More Information
Summary:The invention relates to novel bispecific antigen binding molecules, comprising (a) four moieties capable of specific binding to a costimulatory TNF receptor family member, (b) at least one moiety capable of specific binding to a target cell antigen, and (c) a Fc domain composed of a first and a second subunit capable of stable association, and to methods of producing these molecules and to methods of using the same.
Bibliography:Application Number: US201615280386