INHIBITORS OF HIF PROLYL HYDROXYLASE

The present invention concerns compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such...

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Main Authors LIU RONGQIANG, WANG LIPING, DUBOIS BYRON GABRIEL, LIU PING, SINZ CHRISTOPHER, CAI JIAQIANG, CRESPO ALEJANDRO, DU XIAOXING, QUAN WEIGUO
Format Patent
LanguageEnglish
Published 10.08.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention concerns compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.
Bibliography:Application Number: US201515514537