PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ANGIOEDEMA, CONTAINING EXTRACT OF PEONY ROOT OR MIXTURE OF PEONY ROOT AND LICORICE AS ACTIVE INGREDIENT

The present invention relates to a pharmaceutical composition for preventing or treating angioedema, containing as an active ingredient a peony root extract or an extract of a mixture of peony root and licorice. In particular, the extract of a mixture of peony root and licorice according to the pres...

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Main Authors KIM Junghyun, KIM Jin Sook, LEE Ik Soo, JUNG Dong Ho, CHOI Sojin, KIM Chan-Sik, KIM Young Sook, JUNG Seung-Hyun, PYUN Bo-Jeong, LEE Yun Mi, SHON Eunjin
Format Patent
LanguageEnglish
Published 27.07.2017
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Summary:The present invention relates to a pharmaceutical composition for preventing or treating angioedema, containing as an active ingredient a peony root extract or an extract of a mixture of peony root and licorice. In particular, the extract of a mixture of peony root and licorice according to the present invention inhibits the excessive generation of advanced glycation end products, which may cause macular degeneration, inhibits blood-retinal barrier breakdown causing retinal edema in various animal models, protects or treats a subretinal region causing dry macular degeneration, inhibits angiogenesis causing wet macular degeneration, and thus can be usefully used as an active ingredient for the composition for preventing and treating angioedema including macular degeneration, macular edema, retinal edema, or varicose veins.
Bibliography:Application Number: US201515313654