RETINOID-LIPID DRUG CARRIER

What is described is a pharmaceutical composition for treating a fibrotic disease comprising a drug carrier, which comprises a lipid and a retinoid, and a double-stranded nucleic acid molecule, which comprises an antisense sequence to mRNA encoding human hsp47.

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Bibliographic Details
Main Authors Niitsu Yoshiro, Kalinski Hagar, Minomi Kenjiro, Ahmadian Mohammad, Tanaka Yasunobu, Gaudette John A, Karmali Priya, Liu Yun, Feinstein Elena, Hou Zheng, Mett Igor, Witte Richard P, Payne Joseph E, Ying Wenbin, Perelman Loren A, Avkin-Nahum Sharon, Knopov Victor, Akopian Violetta, Nagarajan Sridhar C
Format Patent
LanguageEnglish
Published 23.03.2017
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
SUGARS
VINEGAR
WINE
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Summary:What is described is a pharmaceutical composition for treating a fibrotic disease comprising a drug carrier, which comprises a lipid and a retinoid, and a double-stranded nucleic acid molecule, which comprises an antisense sequence to mRNA encoding human hsp47.
Bibliography:Application Number: US201615284494