SUSTAINED RELEASE ORAL DOSAGE FORM CONTAINING DALFAMPRIDINE

The present invention provides a sustained release oral dosage form containing dalfampridine that can be administered once daily. The dosage form includes dalfampridine as the active pharmaceutical ingredient and the excipients comprising osmotic agents in a tablet core. The sustained release oral d...

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Bibliographic Details
Main Authors HUANG Shih-Wei, CHANG Chieh-Wen, CHANG Cheng-Wei, WU Jen-Sen, YANG Chih-Yao, TSAI Yi-Chen
Format Patent
LanguageEnglish
Published 16.03.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides a sustained release oral dosage form containing dalfampridine that can be administered once daily. The dosage form includes dalfampridine as the active pharmaceutical ingredient and the excipients comprising osmotic agents in a tablet core. The sustained release oral dosage form of the present invention can be administrated once daily and can provide a proper fluctuation index to reduce undesired adverse effect, prevent alcohol-induced dose dumping and release drug at a rate sufficient to maintain certain drug plasma concentration.
Bibliography:Application Number: US201615256636