MMP-8 ACTIVATION PRODUCT, ITS DETERMINATION AND USE

MMP-8 activation products are disclosed that have a MMP-8 middle-part activation product having a size between 20-35 kDa. Methods of detecting the MMP-8 activation product or activated MMP-8 fragments in a biological sample derived from a subject are also disclosed. The MMP-8 activation product or a...

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Bibliographic Details
Main Authors MAIER Kurt, KORVUO Armi, RÅMAN Ismo, GIESELMANN Dirk-Rolf, MÄNTYLÄ Päivi, TIISALA Sinikka, SORSA Timo
Format Patent
LanguageEnglish
Published 26.01.2017
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Summary:MMP-8 activation products are disclosed that have a MMP-8 middle-part activation product having a size between 20-35 kDa. Methods of detecting the MMP-8 activation product or activated MMP-8 fragments in a biological sample derived from a subject are also disclosed. The MMP-8 activation product or activated MMP-8 fragments diagnose diseases based on abnormal or elevated levels of activated MMP-8.
Bibliography:Application Number: US201515121801