POLYMERIC SYSTEMS AND USES THEREOF IN THERANOSTIC APPLICATIONS

Polymeric systems useful for theranostic applications are disclosed. The polymeric systems comprise a fluorescent or fluorogenic moiety and a therapeutically active agent, each attached to the same or different polymeric moiety. The polymeric systems are designed such that a fluorescent signal is ge...

Full description

Saved in:
Bibliographic Details
Main Authors BLAU Rachel, KISIN-FINFER Einat, REDY-KEISAR Orit, SHABAT Doron, BAABUR-COHEN Hemda, FERBER Shiran, EPSHTEIN Yana, SATCHI-FAINARO Ronit
Format Patent
LanguageEnglish
Published 19.01.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:Polymeric systems useful for theranostic applications are disclosed. The polymeric systems comprise a fluorescent or fluorogenic moiety and a therapeutically active agent, each attached to the same or different polymeric moiety. The polymeric systems are designed such that a fluorescent signal is generated in response to a chemical event, preferably upon contacting an analyte (e.g., an enzyme) that is over-expressed in a diseased tissue or organ. Probes useful for inclusion in such polymeric systems, processes of preparing such probes and the polymeric systems, and uses thereof in diagnostic and/or theranostic applications are also disclosed.
Bibliography:Application Number: US201515124360