Imidazothiazole Derivatives as Modulators of TNF Activity

A series of substituted imidazo[2,1-b]thiazole derivatives, and analogues thereof, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerat...

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Bibliographic Details
Main Authors Jackson Victoria Elizabeth, Alexander Rikki Peter, Ali Mezher Hussein, Brown Julien Alistair
Format Patent
LanguageEnglish
Published 29.12.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A series of substituted imidazo[2,1-b]thiazole derivatives, and analogues thereof, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
Bibliography:Application Number: US201415038986