TETRASUBSTITUTED ALKENE COMPOUNDS AND THEIR USE

Disclosed herein are compounds, or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable salts thereof. The breast canc...

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Main Authors BOCK Mark, ZHU Ping, KORPAL Manav, SAMAJDAR Susanta, HAO Ming-Hong, NYAVANANDI Vijay Kumar, PUYANG Xiaoling, ZHENG Guo Zhu, SMITH Peter Gerard, WANG John
Format Patent
LanguageEnglish
Published 01.12.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Disclosed herein are compounds, or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable salts thereof. The breast cancer may be an ER-positive breast cancer and/or the subject in need of treatment may express a mutant ER-α protein.
Bibliography:Application Number: US201615167373