SULFUR-CONTAINING HETEROCYCLIC DERIVATIVE HAVING BETA SECRETASE INHIBITORY ACTIVITY

The following compound is provided as an agent for treating a disease induced by production, secretion and/or deposition of amyloid ² protein, for example,. a compound represented by the formula (I): wherein ruing A is an optionally substituted carbocyclic group or an optionally substituted heterocy...

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Main Authors HORI Akihiro, KOORIYAMA Yuuji, MATSUMOTO Sae, FUJIKOSHI Chiaki, KATO Terukazu, YONEZAWA Shuji, UENO Tatsuhiko
Format Patent
LanguageEnglish
Published 10.11.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The following compound is provided as an agent for treating a disease induced by production, secretion and/or deposition of amyloid ² protein, for example,. a compound represented by the formula (I): wherein ruing A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group, R 1 is optionally substituted lower alkyl or the like, R 2a and R 2b are each independently hydrogen, optionally substituted lower alkyl or the like, R 3a and R 3c are each independently hydrogen, halogen, hydroxy, optionally substituted lower alkyl or the like, or a pharmaceutically acceptable salt thereof, or a solvate thereof.
Bibliography:Application Number: US201615222567