Autoimmune Antigens and Cancer

Autoimmune diseases are thought to be initiated by exposures to foreign antigens that cross-react with endogenous molecules. Analyses of peripheral blood lymphocytes and serum suggested that mutations in autoimmune antigen targets sparked cellular immunity and cross-reactive humoral immune responses...

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Main Authors Papadopoulos Nickolas, Vogelstein Bert, Rosen Anthony, Casciola-Rosen Livia A, Darrah Erika, Shah Ami A, Joseph Christine, Kinzler Kenneth W
Format Patent
LanguageEnglish
Published 20.10.2016
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Autoimmune diseases are thought to be initiated by exposures to foreign antigens that cross-react with endogenous molecules. Analyses of peripheral blood lymphocytes and serum suggested that mutations in autoimmune antigen targets sparked cellular immunity and cross-reactive humoral immune responses. Acquired immunity to autoimmune antigens can help control naturally occurring cancers.
Bibliography:Application Number: US201415101174