INHIBITORS OF INFLUENZA VIRUSES REPLICATION

Polymorphic forms of Compound (1) or a pharmaceutically acceptable salt thereof, wherein Compound (1) is represented by the following structural formula: are Form A of HCl salt of Compound (1).½H2O, Form F of HCl salt of Compound (1).3H2O, Form D of HCl salt of Compound (1), Form A of Compound (1),...

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Main Authors Jones Steven, Macikenas Dainius, Jurkauskas Valdas, Shi Yi, Tsai Wanjung, Asmal Mohammed, Medek Ales, Mudunuri Praveen, Nti-Addae Kwame W, Ledeboer Mark Willem, O'Neil Simon Adam, Byrn Randal, Waldo Michael, Van Alsten John Gregg, Robertson Sarah Marie
Format Patent
LanguageEnglish
Published 01.09.2016
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Summary:Polymorphic forms of Compound (1) or a pharmaceutically acceptable salt thereof, wherein Compound (1) is represented by the following structural formula: are Form A of HCl salt of Compound (1).½H2O, Form F of HCl salt of Compound (1).3H2O, Form D of HCl salt of Compound (1), Form A of Compound (1), and Form A of tosylate salt of Compound (1). Such polymorphic forms are employed for treating influenza, inhibiting the replication of influenza viruses, or reducing the amount of influenza viruses in a biological sample or in a subject.
Bibliography:Application Number: US201615150459