NITROGEN-CONTAINING BICYCLIC AROMATIC HETEROCYCLIC COMPOUND

On the basis of a cathepsin S inhibitory effect, an excellent agent for treating or preventing autoimmune disease, allergic disease, graft rejection of an organ, bone marrow or tissue, systemic lupus erythematosus, or the like is provided. It was found that a nitrogen-containing bicyclic heterocycli...

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Bibliographic Details
Main Authors Takasuna Yuji, Nakajima Yutaka, Sato Junji, Aoyama Naohiro, Shirakami Shohei, Nigawara Takahiro, Kubo Kaori, Nakanishi Keita, Shirai Fumiyuki, Imada Sunao
Format Patent
LanguageEnglish
Published 11.08.2016
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:On the basis of a cathepsin S inhibitory effect, an excellent agent for treating or preventing autoimmune disease, allergic disease, graft rejection of an organ, bone marrow or tissue, systemic lupus erythematosus, or the like is provided. It was found that a nitrogen-containing bicyclic heterocyclic compound has an excellent cathepsin S inhibitory effect, thereby completing the invention. The compound of the present invention has an cathepsin S inhibitory effect, and can be used as an agent for preventing and/or treating autoimmune disease, allergic disease, graft rejection of an organ, bone marrow or tissue, systemic lupus erythematosus, or the like.
Bibliography:Application Number: US201615017914