ANTI-PCSK9 COMPOUNDS AND METHODS FOR THE TREATMENT AND/OR PREVENTION OF CARDIOVASCULAR DISEASES

Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hyper...

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Main Authors ABDEL-MEGUID SHERIN SALAHELDIN, MARTINEZ ROGELIO, MEYERS HAROLD, BLASS BENJAMIN, MOUSA SHAKER A, CHILDERS WAYNE, ELSHOURBAGY NABIL, ABOU-GHARBIA MAGID, GHIDU VICTOR
Format Patent
LanguageEnglish
Published 31.12.2015
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.
Bibliography:Application Number: US201414767126