POLYMERIC PARTICLES-BASED TEMOZOLOMIDE DOSAGE FORM

The invention relates to pharmacology and medicine, and more specifically to slow-release antitumor drug composition based on biodegradable poly(lactic-co-glycolic acid) (PLGA). The composition comprises temozolomide (TMZ) as the active ingredient and comprises, in addition, surface-active material...

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Bibliographic Details
Main Authors SEVERIN EVGENIJ, GULENKO VICTOR, VASILENKO EKATERINA, IURCHENKO MAKSIM, VORONTSOV EVGENY, MITROKHIN MAXIM
Format Patent
LanguageEnglish
Published 19.11.2015
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to pharmacology and medicine, and more specifically to slow-release antitumor drug composition based on biodegradable poly(lactic-co-glycolic acid) (PLGA). The composition comprises temozolomide (TMZ) as the active ingredient and comprises, in addition, surface-active material and a cryoprotectant as parts of nanoparticles.
Bibliography:Application Number: US201314650799