BIOCATALYST FOR CONVERSION OF METHANE AND METHANOL TO ISOPRENE
Meythylotrophic cells and in particular methanotrophic bacterial cells are genetically engineered to produce isoprene from methane and/or methanol by expressing a heterologous isoprene synthase, and increasing activity of isopentenyl diphosphate isomerase. In addition, upstream DXP pathway enzymes m...
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Main Authors | , , |
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Format | Patent |
Language | English |
Published |
13.08.2015
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Subjects | |
Online Access | Get full text |
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Summary: | Meythylotrophic cells and in particular methanotrophic bacterial cells are genetically engineered to produce isoprene from methane and/or methanol by expressing a heterologous isoprene synthase, and increasing activity of isopentenyl diphosphate isomerase. In addition, upstream DXP pathway enzymes may have increased activity, enzymes in pathways downstream of IPP and DMAPP may have decreased activity, and methane/methanol assimilation pathway enzymes may have increased activity. |
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Bibliography: | Application Number: US201514618066 |