METHOD FOR PREPARING MICROSPHERES FOR EMBOLI, AND METHOD FOR PREPARING MICROSPHERES TO WHICH DRUG-CONTAINING CARRIER IS BOUND

This disclosure relates to microspheres emboli and method of making them. The recoverability of lyophilized microspheres is optimized by adding trehalose prior to lyophilization of the microspheres and vortexing the lyophilized microspheres. The optimization can be useful in maintaining physical pro...

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Bibliographic Details
Main Authors KIM HYEONG MIN, LEE GA HYEON, LEE JAE HWI, KWAK BYUNG KOOK
Format Patent
LanguageEnglish
Published 13.08.2015
Subjects
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
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Summary:This disclosure relates to microspheres emboli and method of making them. The recoverability of lyophilized microspheres is optimized by adding trehalose prior to lyophilization of the microspheres and vortexing the lyophilized microspheres. The optimization can be useful in maintaining physical properties, shapes, and the drug release level of the microspheres for emboli. Chitosan microspheres can be useful in stably causing emboli in blood vessels, and precisely adjusting the release of a drug, and thus can be used in anticancer treatment.
Bibliography:Application Number: US201314424988