Antibodies to Non-Functional Oligomeric P2X7 Receptors

The invention relates to purinergic receptors, to antibodies and related fragments thereof for binding to said receptors, to production of said antibodies and fragments and to sue of said antibodies and fragments for cancer detection and therapy. In particular the antibodies described bind specifica...

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Bibliographic Details
Main Authors PILKINGTON GLENN RONALD, BARDEN JULIAN ALEXANDER, GIDLEY-BAIRD ANGUS
Format Patent
LanguageEnglish
Published 06.08.2015
Subjects
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Summary:The invention relates to purinergic receptors, to antibodies and related fragments thereof for binding to said receptors, to production of said antibodies and fragments and to sue of said antibodies and fragments for cancer detection and therapy. In particular the antibodies described bind specifically to non-functional P2X& receptors expressed by live cells.
Bibliography:Application Number: US201414456898