MAGNETIC CORE-SHELL PARTICLES WITH HIGH SEPARATION EFFICIENCY

• Main Authors: KRESS PETER, MICHEL DE AREVALO AYMEE LISETTE, HERZOG HARALD, MEYER JUERGEN, KATUSIC STIPAN
• Format: Patent
• Language: English
• Published: 30.07.2015
• Subjects: APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TO SURFACES, IN GENERAL; BEER; BIOCHEMISTRY; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PROCESSES FOR APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TOSURFACES, IN GENERAL; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; SPRAYING OR ATOMISING IN GENERAL; THEIR RELEVANT APPARATUS; TRANSPORTING; VINEGAR; WINE

Functionalized magnetic core-shell particles which are present predominantly in the form of isolated, essentially spherical individual particles, the core of which consists essentially of one or more magnetic iron oxides, the shell of which consists essentially of impervious, amorphous silicon dioxide, and the functionalization of which consists of amino or epoxy group units on the surface of the particles, and which additionally have a mean particle diameter d50 such that 2<d50<10 μm, the particles have a content of iron oxide of 83 to 92% by weight, of silicon dioxide of 5 to 15% by weight, and of carbon of 0.5 to 3% by weight, the amino or epoxy group is part of the structural unit -OSi-alkyl-X where X is NH2 or epoxy and alkyl is C2-C8, and the concentration of the amino groups or of the epoxy groups is at least 30 μmol/g of particles. The particles are used for immobilization of enzymes.