MOBILE VESSEL OR CARRIER FOR THE MANUFACTURING PRODUCTION, PURIFICATION AND STERILE FILL AND FINISH OF BIOLOGICS

A mobile biologics production system can include a mobile carrier configured to be trailered to a biologics production location. The mobile carrier defines an interior volume configured to provide an aseptic environment for manufacturing, production, and purification of biologics. A production sub-s...

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Bibliographic Details
Main Authors GUERINI MICHAEL NICHOLAS, KEENE ROBERT O
Format Patent
LanguageEnglish
Published 11.06.2015
Subjects
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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Summary:A mobile biologics production system can include a mobile carrier configured to be trailered to a biologics production location. The mobile carrier defines an interior volume configured to provide an aseptic environment for manufacturing, production, and purification of biologics. A production sub-system disposed in the interior volume includes a single-use bioreactor configured to grow biologics which can include microbes, mammalian cell lines, insect cell lines, and plant cell lines. The bioreactor is controlled by a controller, and can have a working capacity of less than about 100 L. A purification sub-system disposed in the internal volume is fluidically coupled to the production sub-system and configured to produce a finished biologic product. A sterile fill and finish sub-system is also disposed in the interior volume defined by the mobile carrier and can be configured to produce a final Product ready for use by the end user.
Bibliography:Application Number: US201514621556