COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this inventio...

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Main Authors SANGHVI TAPAN, DAVIS CHRISTOPHER JOHN, ETXEBARRIA I JARDI GORKA, MEDEK ALES, PANESAR MANINDER, SHAW DAVID MATTHEW, ZWICKER CARL, PIERARD FRANCOISE, CHARRIER JEAN-DAMIEN, ZHANG YUEGANG, PEGG SIMON, STUDLEY JOHN, PINDER JOANNE, FRAYSSE DAMIEN, WALDO MICHAEL, ALEM NAZIHA
Format Patent
LanguageEnglish
Published 11.06.2015
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention. The compounds of this invention have formula I-A or I-B: wherein the variables are as defined herein.
Bibliography:Application Number: US201414561368