METHODS AND MATERIALS FOR THE DETECTION OF DENGUE VIRUS INFECTION

The present invention provides monoclonal antibodies that are specific for the Dengue non-structural glycoprotein NS1 in monomeric and/or oligomeric (primarily dimeric) form, together with methods, including ELISA and lateral flow assays, that employ the disclosed antibodies for the early detection...

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Bibliographic Details
Main Authors CHEN HONGJING, MORKOWSKI STANISLAW, HOUGHTON RAYMOND L, RAYCHAUDHURI SYAMAL, STEVENS YVONNE, BOSE MOHUA, NEEDHAM JAMES WILLIAM
Format Patent
LanguageEnglish
Published 26.03.2015
Subjects
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Summary:The present invention provides monoclonal antibodies that are specific for the Dengue non-structural glycoprotein NS1 in monomeric and/or oligomeric (primarily dimeric) form, together with methods, including ELISA and lateral flow assays, that employ the disclosed antibodies for the early detection of Dengue virus infection. Diagnostic kits for the detection of Dengue infection are also provided, such kits including the disclosed monoclonal and/or polyclonal antibodies.
Bibliography:Application Number: US201414566321