IgG2 DISULFIDE ISOFORM SEPARATION

Methods for producing an IgG2 antibody preparation enriched for one of several IgG2 structural isoforms, differing by disulfide connectivity in the hinge region of the antibody, are disclosed.

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Bibliographic Details
Main Authors WOEHLE DIANA, CHEN YAUTYAN, WILTZIUS JED J, DILLON THOMAS M, CHOU YI-TE, BONDARENKO PAVEL
Format Patent
LanguageEnglish
Published 18.12.2014
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Summary:Methods for producing an IgG2 antibody preparation enriched for one of several IgG2 structural isoforms, differing by disulfide connectivity in the hinge region of the antibody, are disclosed.
Bibliography:Application Number: US201214363735