Tricyclic Compounds as Modulators of TNF-alpha Synthesis and as PDE4 Inhibitors

The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-α or by PDE4, including but not limited to rheumatoid arthritis.

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Bibliographic Details
Main Authors GADDAM BAPU, KOSTURA MATTHEW J, GUZEL MUSTAFA, MJALLI ADNAN M.M, POLISETTI DHARMA RAO
Format Patent
LanguageEnglish
Published 18.12.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of conditions or disorders mediated by TNF-α or by PDE4, including but not limited to rheumatoid arthritis.
Bibliography:Application Number: US201414477302