COMPOUNDS FOR THE TREATMENT OF CNS DISORDERS

The invention relates to novel 1,6-disubstituted pyrazolopyrimidinones of formula (I), in which Hc is a tetrahydropyranyl-group and R1 is the group V-W-*, whereby V and W independently of each other may be an aryl group or an heteroaryl group, which independently of each other may optionally be subs...

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Bibliographic Details
Main Authors GIOVANNINI RICCARDO, FOX THOMAS, HEINE NIKLAS, DORNER-CIOSSEK CORNELIA, EICKMEIER CHRISTIAN, FIEGEN DENNIS, SCHAENZLE GERHARD, FUCHS KLAUS, ROSENBROCK HOLGER
Format Patent
LanguageEnglish
Published 27.11.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention relates to novel 1,6-disubstituted pyrazolopyrimidinones of formula (I), in which Hc is a tetrahydropyranyl-group and R1 is the group V-W-*, whereby V and W independently of each other may be an aryl group or an heteroaryl group, which independently of each other may optionally be substituted. According to one aspect of the invention the new compounds are for use as medicaments or for the manufacture of medicaments, in particular medicaments for the treatment of conditions concerning deficits in perception, concentration, learning or memory. The new compounds are also for the manufacture of medicaments and/or for use in the treatment of e.g. Alzheimer's disease, in particular for cognitive impairment associated with Alzheimer's disease.
Bibliography:Application Number: US201314087035