Methods and apparatus for independent control of product and reactant concentrations

A microreactor with a reaction chamber comprising two sub-chambers with reconfigurable volumes, an input conduit with input valve, an un-filtered output conduit with first output valve, and a filtered output conduit with a second output valve is used to perform a method to control a different diluti...

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Bibliographic Details
Main Authors LEE HARRY, LEE KEVIN SHAO-KWAN
Format Patent
LanguageEnglish
Published 21.08.2014
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Summary:A microreactor with a reaction chamber comprising two sub-chambers with reconfigurable volumes, an input conduit with input valve, an un-filtered output conduit with first output valve, and a filtered output conduit with a second output valve is used to perform a method to control a different dilution rate for cells and molecules in continuous culture bioprocesses. In preferred embodiments flow control is achieved using the difference in volume of the two sub-chambers.
Bibliography:Application Number: US201414180403