AMINOQUINOXALINE DERIVATIVES FOR TREATMENT OF NEURODEGENERATIVE DISEASES

The present invention relates to compounds of formula (I) below: for which: -X represents a hydrogen atom, a halogen atom, a group NO2 or NH2, -R0 represents H or -CH2-C≡CH, and -R1 and R2 each represent, independently of one another, a hydrogen atom; a saturated or unsaturated, linear or branched h...

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Main Authors SCHMIDT FANNY, FERRIE LAURENT, LE DOUARON GAËL, RAISMAN-VOZARI RITA, FIGADERE BRUNO
Format Patent
LanguageEnglish
Published 24.04.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention relates to compounds of formula (I) below: for which: -X represents a hydrogen atom, a halogen atom, a group NO2 or NH2, -R0 represents H or -CH2-C≡CH, and -R1 and R2 each represent, independently of one another, a hydrogen atom; a saturated or unsaturated, linear or branched hydrocarbon-based chain comprising from 1 to 10 carbon atoms; or an optionally substituted aryl group, and also the pharmaceutically acceptable salts thereof, the stereoisomers thereof or mixtures of stereoisomers thereof in any proportion, in particular for use thereof as a medicament, in particular in the treatment or prevention of neurodegenerative diseases, and also the processes for the preparation thereof and the pharmaceutical compositions comprising same.
Bibliography:Application Number: US201214008189