Screening Method for the Identification of Agents Capable of Activating CD4+CD25+ Regulatory T-Cells Through Interactions with the HIV-1 GP120 Binding Site on CD4

The present invention relates specific activation of a regulatory T cell via a specific CD4 epitope and uses thereof, e.g. for the treatment of an autoimmune disease or an allergy or asthma or graft rejection or tolerance induction.

Saved in:
Bibliographic Details
Main Authors JONULEIT HELMUT, BOPP TOBIAS, SCHMITT EDGAR, BECKER CHRISTIAN, SCHNEIDER FRANZ-JOSEF
Format Patent
LanguageEnglish
Published 03.04.2014
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
Online AccessGet full text

Cover

More Information
Summary:The present invention relates specific activation of a regulatory T cell via a specific CD4 epitope and uses thereof, e.g. for the treatment of an autoimmune disease or an allergy or asthma or graft rejection or tolerance induction.
Bibliography:Application Number: US201314031919