Viral expression plasmids for production of proteins, antibodies, enzymes, virus-like particles and for use in cell-based assays

This disclosure shows that the EBV FR-element comprised of EBNA1 multimeric binding sites can provide the stable maintenance replication function to the mouse polyomavirus (PyV) core origin plasmids in the presence of BPV-1 E2 protein and PyV large T-antigen (LT).

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Bibliographic Details
Main Authors JANIKSON KADRI, KALLING ANNE, TAGEN INGRID, TOVER ANDRES, TEGOVA RADI, ABROI AARE, USTAV ENE, TOOTS URVE, SILLA TOOMAS, GEIMANEN JELIZAVETA, USTAV MART, MANDEL TIIU
Format Patent
LanguageEnglish
Published 12.09.2013
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Summary:This disclosure shows that the EBV FR-element comprised of EBNA1 multimeric binding sites can provide the stable maintenance replication function to the mouse polyomavirus (PyV) core origin plasmids in the presence of BPV-1 E2 protein and PyV large T-antigen (LT).
Bibliography:Application Number: US201313748017