MORPHOLINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS

The invention relates to morpholine spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

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Bibliographic Details
Main Authors PONTILLO JOSEPH, BINCH HAYLEY MARIE, DENINNO MICHAEL PAUL, GROOTENHUIS PETER DIEDERIK JAN, HADIDA-RUAH SARA SABINA, HILGRAF NICOLE, HURLEY DENNIS JAMES, KALLEL EDWARD ADAM, FANNING LEV TYLER DEWEY, MILLER MARK THOMAS, SILINA ALINA, ARUMUGAM VIJAYALAKSMI, JOSHI PRAMOD, FRIEMAN BRYAN A, SHETH URVI JAGDISHBHAI
Format Patent
LanguageEnglish
Published 18.10.2012
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The invention relates to morpholine spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
Bibliography:Application Number: US201213418737