COMPOSITIONS CONTAINING GLYCOSYLATED ANTIBODIES AND USES THEREOF

• Main Authors: FUJIMORI TARO, CORREIA IVAN R.S, HRUSKA MATTHEW W, PAULSON SUSAN KAYE
• Format: Patent
• Language: English
• Published: 02.08.2012
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention provides compositions of antibodies, e.g., human antibodies, of varying glycosylation structures that serve to achieve desired rates of serum clearance. The invention also provides methods for modulating the pharmacokinetics of antibodies, e.g., human antibodies, and therapeuti...