SUBSTITUTED IMIDAZOHETEROCYCLE DERIVATIVES

The present invention provides substituted imidazoheterocycles having the general structure of formula I: wherein Y is chosen from -O-, -OCRgRh-, -CRgRhO-, -CRgRh-, -(CRgRh)2-, -NRi-, -CRgRhNRi- and -NRiCRgRh-. Also provided are pharmaceutically acceptable salts, acid salts, hydrates, solvates and s...

Full description

Saved in:
Bibliographic Details
Main Authors GUSTAFSON GARY R, RALBOVSKY JANET L, BECKETT R. PAUL, O'CONNOR STEPHEN J, NEWCOM JASON S, LUO ROBERT ZHIYONG
Format Patent
LanguageEnglish
Published 19.01.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present invention provides substituted imidazoheterocycles having the general structure of formula I: wherein Y is chosen from -O-, -OCRgRh-, -CRgRhO-, -CRgRh-, -(CRgRh)2-, -NRi-, -CRgRhNRi- and -NRiCRgRh-. Also provided are pharmaceutically acceptable salts, acid salts, hydrates, solvates and stereoisomers of the compounds of formula I. The compounds are useful as modulators of cannabinoid receptors and for the prophylaxis and treatment of cannabinoid receptor-associated diseases and conditions, such as pain, inflammation and pruritis.
Bibliography:Application Number: US200913126201