METHOD FOR PREPARATION OF N-METHYL-3-(2-TRIBUTYLSTANNYLPHENOXY)-3-PHENYLPROPANAMINE, AND USE THEROF

A method for preparation of N-methyl-3-(2-tributylstannylphenoxy)-3-phenylpropanamine is provided, which includes formation of N-methyl-3-(2-tributylstannylphenoxy)-3-phenylpropanamine, useful as a precursor of a norepinephrine transporter (NET) contrast label [123Iodine](R)-N-methyl-3-(2-iodophenox...

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Bibliographic Details
Main Authors HSU CHENG-FANG, LIN CHENG-HSIEN, LIN TSYH-LANG, CHANG YU, LIU SHOW-WEN
Format Patent
LanguageEnglish
Published 22.12.2011
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:A method for preparation of N-methyl-3-(2-tributylstannylphenoxy)-3-phenylpropanamine is provided, which includes formation of N-methyl-3-(2-tributylstannylphenoxy)-3-phenylpropanamine, useful as a precursor of a norepinephrine transporter (NET) contrast label [123Iodine](R)-N-methyl-3-(2-iodophenoxy)-3-phenylpropanamine ([123I]MIPP) with a leaving group Bu3Sn.
Bibliography:Application Number: US201113087862