Purification Of Biologically-Produced 1,3-Propanediol

A process for purifying 1,3-propanediol from the fermentation broth of a cultured E. coli that has been bioengineered to synthesize 1,3-propanediol from sugar is provided. The basic process entails filtration, ion exchange and distillation of the fermentation broth product stream, preferably includi...

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Main Authors LIEVENSE JEFFERSON C, ADKESSON DENNIS MICHAEL, AMES TYLER T, FITZGIBBON PATRICK, YU EUGENE K, GADDY JAMES M, LUYBEN MICHAEL L, GALLAGHER F. GLENN, DRAVIS BRYAN C, LEHNHARDT WILLIAM F, WENNDT GREGORY M, TROTTER ROBERT E, CHU LUIS ALBERTO, SEAPAN MAYIS, ALSOP ALBERT W, DISNEY JAMES M
Format Patent
LanguageEnglish
Published 23.06.2011
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
SPIRITS
TRANSPORTING
VINEGAR
WINE
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Summary:A process for purifying 1,3-propanediol from the fermentation broth of a cultured E. coli that has been bioengineered to synthesize 1,3-propanediol from sugar is provided. The basic process entails filtration, ion exchange and distillation of the fermentation broth product stream, preferably including chemical reduction of the product during the distillation procedure. Also provided are highly purified compositions of 1,3-propanediol.
Bibliography:Application Number: US201113035246