Sulfonyl-Derivatives as Novel or Histone Deacetylase

This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.

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Bibliographic Details
Main Authors ARTS JANINE, BACKX LEO-JACOBUS JOZEF, VAN HEUSDEN JIMMY ARNOLD VIVIANE, DYATKIN ALEXEY BORISOVICH, VERDONCK MAC GUSTAAF CELINE, MEERPOEL LIEVEN, VAN BRANDT SVEN FRANCISCUS ANNA, VAN EMELEN KRISTOF, PILATTE ISABELLE NOELLE CONSTANCE, DE WINTER HANS LOUIS JOS, PONCELET VIRGINIE SOPHIE
Format Patent
LanguageEnglish
Published 23.09.2010
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Bibliography:Application Number: US20100759256