Multi-Component Inhibitors of Nucleic Acid Polymerases
The present invention provides multi-component inhibitors of nucleic acid polymerases, methods of making, and methods of using same. One component of the multi-component inhibitor is a molecule that binds to a polymerase (i.e., a polymerase-binding molecule (PBM)), but does not thereby substantially...
Saved in:
Main Authors | , |
---|---|
Format | Patent |
Language | English |
Published |
19.08.2010
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The present invention provides multi-component inhibitors of nucleic acid polymerases, methods of making, and methods of using same. One component of the multi-component inhibitor is a molecule that binds to a polymerase (i.e., a polymerase-binding molecule (PBM)), but does not thereby substantially inhibit its polymerase activity. Another component is a molecule or complex of molecules that binds to a PBM (i.e., a PBM-binding molecule). The combination of the PBM and PBM-binding molecule/complex substantially inhibits polymerase activity. |
---|---|
Bibliography: | Application Number: US20090636655 |