Microtiter plate to mitigate cell distribution bias from meniscus edge

A lid assembly is provided for mitigation or removal of meniscus along the periphery of sample liquid in the cavity wells of a microtiter plate. The assembly includes a lid plate having a mount surface, an array of plugs corresponding to the array of wells, and a plurality of posts. Each plug extend...

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Bibliographic Details
Main Authors GUTTING BRADFORD W, ANDREWS, JR. GEORGE A, MACKIE RYAN S
Format Patent
LanguageEnglish
Published 05.08.2010
Subjects
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
CHEMISTRY
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SPIRITS
TRANSPORTING
VINEGAR
WINE
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Summary:A lid assembly is provided for mitigation or removal of meniscus along the periphery of sample liquid in the cavity wells of a microtiter plate. The assembly includes a lid plate having a mount surface, an array of plugs corresponding to the array of wells, and a plurality of posts. Each plug extends below from the mount surface and is insertable into the periphery of a counterpart well for contact with the liquid. The plurality of posts suspends the lid plate above the microtiter plate. Each post optionally passes through an orifice through the mount surface, with each post including an adjustable clamp to support the lid plate. The mount surface optionally includes an array of cavities that correspond in disposition to the array of plugs. Each plug is independently insertable through the mount surface to adjust depth of each plug into its counterpart well.
Bibliography:Application Number: US20090322958