Imaging probes

The present invention relates to molecular probes of the formula (I) {L1-R1-L}n-A-CO-NH-R2-L2  (I) as defined herein that allow for the observation of the catalytic activity of a selected cathepsin in in vitro assays, in cells or in multicellular organisms, a method for their preparation and the use...

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Bibliographic Details
Main Authors KINDERMANN MAIK, GLOBISCH ANJA, WENDT KARL-ULRICH
Format Patent
LanguageEnglish
Published 29.07.2010
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to molecular probes of the formula (I) {L1-R1-L}n-A-CO-NH-R2-L2  (I) as defined herein that allow for the observation of the catalytic activity of a selected cathepsin in in vitro assays, in cells or in multicellular organisms, a method for their preparation and the use thereof.
Bibliography:Application Number: US20090549017