PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS

Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): wherein x, y, W, V, R1, R2, R3, R4, R5, R6, R7, R7a, R8, R8a, R9, R9a, R10 and R10a are defined h...

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Main Authors SUN SHAOYI, HARVEY DANIEL F, ZHANG ZAIHUI, ABREO MELWYN, GSCHWEND HEINZ W, TU CHI, KONDRATENKO MIKHAIL A, KODUMURU VISHNUMURTHY, HUDSON CINDY J, KAMBOJ RAJENDER, BAGHERZADEH MEHRAN SEID, WINTHER MICHAEL D, LIU SHIFENG, RAINA VANDNA, SVIRIDOV SERGUEI, LI WENBAO
Format Patent
LanguageEnglish
Published 25.02.2010
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): wherein x, y, W, V, R1, R2, R3, R4, R5, R6, R7, R7a, R8, R8a, R9, R9a, R10 and R10a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Bibliography:Application Number: US20090552868