In Vitro Assay Based on Camp Levels Modulated by Gi-Coupled Receptors

The present invention relates to a reliable and effective in vitro assay based on cAMP levels modulated by Gi-coupled receptors expressed in a selected cell for screening and identifying pharmaceutically effective compounds that specifically interact with and modulate the activity of a cellular rece...

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Bibliographic Details
Main Authors PERNELLE CHRISTINE, WANG SHUREN, FOUCHAQ BENOIT, PIWNICA DAVID
Format Patent
LanguageEnglish
Published 10.12.2009
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Summary:The present invention relates to a reliable and effective in vitro assay based on cAMP levels modulated by Gi-coupled receptors expressed in a selected cell for screening and identifying pharmaceutically effective compounds that specifically interact with and modulate the activity of a cellular receptor.
Bibliography:Application Number: US20070308127