INDOLE, BENZIMIDAZOLE, AND BENZOLACTAM BORONIC ACID COMPOUNDS, ANALOGS THEREOF AND METHODS OF USE THEREOF

Benzimidazole, indole and benzolactam boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-alpha) in a subject in need thereof.

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Bibliographic Details
Main Authors LI FRANCINE F, DYAKONOV TATYANA, VANVLIET DAVID N, BURNS JAMES F, DIDSBURY JOHN R, JONES MICHAEL L, MATTHEW JESSY, SCHOENEN FRANK J, HAYDAR SIMON N, SCICINSKI JAN J, MIDDLEMISS DAVID, CABANA LEONARD A, MARKWORTH CHRISTOPHER J, COLLUPY GLENN C
Format Patent
LanguageEnglish
Published 22.10.2009
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Benzimidazole, indole and benzolactam boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-alpha) in a subject in need thereof.
Bibliography:Application Number: US20080268237