Antineoplastic compounds and pharmaceutical compositions thereof

Chemical compounds derived by in silico molecular modelling, having a well defined structure suitable for the blocking of the phosphorylation event, through the specific interaction of the chemical with the Casein Kinase 2 enzyme substrate phosphorylation domain or it's neighbourhood. This inve...

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Main Authors RODRIGUEZ FERNANDEZ ROLANDO EDUARDO, ALVAREZ ROBERTO VERA, PEREA RODRIGUEZ SILVIO ERNESTO, GOMEZ RAIMUNDO UBIETA, NUEZ VEULENS ANIA DE LA, LASA ALEXIS MUSACCHIO, REYES YULIET MAZOLA, ACEVEDO CASTRO BORIS ERNESTO
Format Patent
LanguageEnglish
Published 27.08.2009
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Chemical compounds derived by in silico molecular modelling, having a well defined structure suitable for the blocking of the phosphorylation event, through the specific interaction of the chemical with the Casein Kinase 2 enzyme substrate phosphorylation domain or it's neighbourhood. This invention comprises also the pharmaceutical compositions containing such compounds, and their use in the preparation of medicines or agents for the treatment of diseases or conditions related with neoplastic processes.
Bibliography:Application Number: US20060920031