Self-Emulsifying Formulations of CETP Inhibitors

A liquid formulation for oral administration of the CETP inhibitor of formula (I) has improved bioavailability compared with conventional solid formulations. The formulation comprises the CETP inhibitor, or a pharmaceutically acceptable salt thereof; an oil; and one or more nonionic surfactants havi...

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Bibliographic Details
Main Authors SHETH AGAM R, GHOSH SOUMOJEET, ALANI LAMAN L, REGE BHAGWANT, CRUANES MARIA T, MCKELVEY CRAIG A
Format Patent
LanguageEnglish
Published 23.07.2009
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A liquid formulation for oral administration of the CETP inhibitor of formula (I) has improved bioavailability compared with conventional solid formulations. The formulation comprises the CETP inhibitor, or a pharmaceutically acceptable salt thereof; an oil; and one or more nonionic surfactants having a hydrophilic lipophilic balance (HLB)>10.
Bibliography:Application Number: US20060085745